Below is a list of publications that have been supported through funding by IISAGE.
2025

Sex differences in DNA methylation in bats
Jack G. Rayner, Samantha L. Bock, Andrew J. Lonski, Nicole C. Riddle, Gerald S. Wilkinson bioRxiv 2025.05.13.653776;

Sex Differences in Telomere Length in a Bat With Female-Biased Longevity
Rayner, J.G., Marshall, A., Adams, D.M., Kaiser, J., Armenta, K. and Wilkinson, G.S. (2025), Sex Differences in Telomere Length in a Bat With Female-Biased Longevity. Ecol Evol, 15: e71378.

DNA Methylation Dynamics Reflect Sex and Status Differences in Mortality Rates in a Polygynous Bat
Adams, D.M., Rayner, J.G., Hex, S.B.S.W. and Wilkinson, G.S. (2025), DNA Methylation Dynamics Reflect Sex and Status Differences in Mortality Rates in a Polygynous Bat. Mol Ecol, 34: e17745.

Comparative Transcriptomic Analysis of Embryonic Stem Cells (ESCs) across Mammalian Species
Yifei Fang, Yue Su, Richard Meisel, James R Walters, Tony Gamble, Eric C. Randolph, Xingtan Yu, Meihong Shi, Guangsheng Li, Jingzhi Zhang, IISAGE Consortium, Xiuchun (Cindy) Tian, Yong Tang, Jingyue (Ellie) Duan bioRxiv 2025.03.11.642582;

Sex-biased Transcriptome in in vitro Produced Bovine Early Embryos
Meihong Shi, Guangsheng Li, Hannah Marie Araujo, Angie S Lee, Jingzhi Zhang, Yoke Lee Lee, IISAGE Consortium, Soon Hon Cheong, Jingyue (Ellie) Duan
bioRxiv 2025.03.04.641446;

TimeFlies: an snRNA-seq aging clock for the fruit fly head sheds light on sex-biased aging
Nikolai Tennant, Ananya Pavuluri, Kate O’Connor -Giles, Gunjan Singh, Erica Larschan, Ritambhara Singh bioRxiv 2024.11.25.625273;
2024

Sex-biased gene content is associated with sex chromosome turnover in Danaini butterflies
Pablo Mora, Monika Hospodářská, Anna Chung Voleníková, Petr Koutecký, Jana Štundlová, Martina Dalíková, James R. Walters, Petr Nguyen. Sex-biased gene content is associated with sex chromosome turnover in Danaini butterflies. Mol Ecol (2024). doi: https://doi.org/10.1111/mec.17256

Comparative transcriptomic analysis of bovine mesenchymal stromal cells reveals tissue-source and species-specific differences
Nikola Danev, Guangsheng Li, Jingyue Ellie Duan, Gerlinde R Van de Walle. Comparative transcriptomic analysis of bovine mesenchymal stromal cells reveals tissue-source and species-specific differences. iScience. (2024).

Resistance to age-related hearing loss in the echolocating big brown bat (Eptesicus fuscus)
Grace Capshaw, Clarice A. Diebold, Danielle M. Adams, Jack G. Rayner, Gerald S. Wilkinson, Cynthia F. Moss and Amanda M. Lauer. Resistance to age-related hearing loss in the echolocating big brown bat (Eptesicus fuscus). Proc Biol Sci. (2024).

Hallmarks of aging: A user’s guide for comparative biologists
Peggy R Biga, Jingyue E Duan, Tristan E Young, Jamie R Marks, Anne Bronikowski, Louis P Decena, Eric C Randolph, Ananya G Pavuluri, Guangsheng Li, Yifei Fang, Gerald S Wilkinson, Gunjan Singh, Nathan T Nigrin, Erica N Larschan, Andrew J Lonski, Nicole C Riddle, IISAGE Consortium. Hallmarks of aging: A user’s guide for comparative biologists. Ageing Research Reviews. (2024).
2023

Comparative analysis of animal lifespan
Nicole C. Riddle, Peggy R. Biga, Anne M. Bronikowski, James R. Walters, Gerald S. Wilkinson & IISAGE Consortium. Comparative analysis of animal lifespan. GeroScience (2023).

CellBiAge: Improved single-cell age classification using data binarization
Doudou Yu, Manlin Li, Guanjie Linghu, Yihuan Hu, Kaitlyn H. Hajdarovic, An Wang, Ritambhara Singh, Ashley E. Webb. CellBiAge: Improved single-cell age classification using data binarization. Cell Rep (2023).
2022

Sex-specific aging in animals: Perspective and future directions
Anne M. Bronikowski, Richard P. Meisel, Peggy R. Biga, James R. Walters, Judith E. Mank, Erica Larschan, Gerald S. Wilkinson, Nicole Valenzuela, Ashley Mae Conard, João Pedro de Magalhães, Jingyue (Ellie) Duan, Amy E. Elias, Tony Gamble, Rita M. Graze, Kristin E. Gribble, Jill A. Kreiling, Nicole C. Riddle. Sex-specific aging in animals: Perspective and future directions. Aging Cell (2022).